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UFC 121: Lesnar vs. Velasquez
Preliminary card
- Heavyweight bout:
Jon Madsen vs. 
Gilbert Yvel
- Madsen defeated Yvel via TKO (punches) at 1:48 of round 1. This bout aired on the live broadcast following the Lesnar vs. Velasquez fight.
- Middleweight bout: Chris Camozzi vs.
Dong Yi Yang
- Camozzi defeated Yang via split decision (28-29, 29-28, 29-28).
- Lightweight bout:
Sam Stout vs. 
Paul Taylor
- Stout defeated Taylor via split decision (29-28, 28-29, 30-27).
- Welterweight bout: Mike Guymon vs. Daniel Roberts
- Roberts defeated Guymon via submission (anaconda choke) at 1:13 of round 1. This bout aired last on the live broadcast following the Lesnar vs. Velasquez fight.
Preliminary card (Spike TV)
- Middleweight bout: Patrick Côté vs. Tom Lawlor
- Lawlor defeated Côté via unanimous decision (30-27, 30-27, 30-27).
- Middleweight bout: Court McGee vs. Ryan Jensen
- McGee defeated Jensen via submission (arm triangle choke) at 1:21 of round 3.
Main card
- Heavyweight bout: Brendan Schaub vs.
Gabriel Gonzaga
- Schaub defeated Gonzaga via unanimous decision (30-27, 30-27, 30-27).
- Light Heavyweight bout: Tito Ortiz vs. Matt Hamill
- Hamill defeated Ortiz via unanimous decision (29-28, 29-28, 30-27).
- Welterweight bout: Diego Sanchez vs. Paulo Thiago
- Sanchez defeated Thiago via unanimous decision (30-26, 29-28, 29-28).
- Welterweight bout: Jake Shields vs.
Martin Kampmann
- Shields defeated Kampmann via split decision (28-29, 29-28, 30-27).
- Heavyweight Championship bout: Brock Lesnar (c) vs Cain Velasquez
- Velasquez defeated Lesnar via TKO (punches) at 4:12 of round 1 to become the new UFC Heavyweight Champion.
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