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UFC 81: Breaking Point
Preliminary card
- Lightweight bout:
Rob Emerson vs. 
Keita Nakamura
- Emerson defeated Nakamura via split decision (30-27, 28-29, 30-27). This bout aired last on the PPV broadcast following the Lytle vs. Bradley fight.
- Light heavyweight bout: David Heath vs. Tim Boetsch
- Boetsch defeated Heath via TKO (strikes) at 4:52 of Round 1. This bout aired on the PPV broadcast following the Marquardt vs. Horn fight.
- Middleweight bout: Marvin Eastman vs. Terry Martin
- Eastman defeated Martin via unanimous decision (29–28, 30–27, 30–27).
- Welterweight bout: Chris Lytle vs. Kyle Bradley
- Lytle defeated Bradley via TKO (strikes) at 0:33 of Round 1. This bout aired on the PPV broadcast following the Sylvia vs. Nogueira fight.
Main card
- Lightweight bout: Tyson Griffin vs.
Gleison Tibau
- Griffin defeated Tibau via unanimous decision (30–27, 30-27, 30-27).
- Middleweight bout: Ricardo Almeida vs. Rob Yundt
- Almeida defeated Yundt via submission (guillotine choke) at 1:08 of Round 1. Yundt was a late replacement for Alan Belcher, who had to withdraw from the bout due to a severe case of bronchitis.
- Middleweight bout: Nate Marquardt vs. Jeremy Horn
- Marquardt defeated Horn via submission (guillotine choke) at 1:37 of Round 2.
- Heavyweight bout: Brock Lesnar vs. Frank Mir
- Mir defeated Lesnar via submission (knee bar) at 1:30 of round 1.
- Interim Heavyweight Championship bout: Tim Sylvia vs. Antônio Rodrigo Nogueira
- Nogueira defeated Sylvia via submission (guillotine choke) at 1:28 of Round 3 to become UFC Interim Heavyweight Champion.